| 10/8/2025 | Seattle Mariners (3)
Detroit Tigers (9) | Detroit Tigers | 12 | | Money Line: | Detroit Tigers | Winner | | Spread: | No Pick | - | | Total: | No Pick | - |
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| 10/8/2025 | Milwaukee Brewers (3)
Chicago Cubs (4) | Chicago Cubs | 7 | | Money Line: | Milwaukee Brewers | Loser | | Spread: | No Pick | - | | Total: | No Pick | - |
|
| 10/8/2025 | Toronto Blue Jays (5)
New York Yankees (2) | Toronto Blue Jays | 7 | | Money Line: | No Pick | - | | Spread: | Toronto Blue Jays (+1.5) | Winner | | Total: | No Pick | - |
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| 10/8/2025 | Philadelphia Phillies (8)
Los Angeles Dodgers (2) | Philadelphia Phillies | 10 | | Money Line: | No Pick | - | | Spread: | Los Angeles Dodgers (-1.5) | Loser | | Total: | No Pick | - |
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